Buy Premarin Tablet 0.625 mg are a form of hormone replacement therapy (HRT), used to treat symptoms of the menopause. Premarin contains conjugated oestrogens, which emulate the female sex hormone oestrogen. During the menopause, the production of oestrogen in a woman’s ovaries gradually stops. This deficiency can lead to a number of symptoms, including hot flushes, depression, sleep problems, dryness and osteoporosis.